Novel Therapeutic Strategies for Oral Squamous Cell Carcinoma-An Overview

Surgery, radiotherapy, and chemotherapy have been the mainstay of oral squamous cell carcinoma (OSCC) management. However, these treatments often come with significant side effects and limitations, including systemic toxicity and drug resistance. Recent advancements in therapeutic strategies for oral cancer have focused on more targeted and less invasive approaches. Some of the novel therapeutic strategies for OSCC include immunotherapy, targeted therapy, photodynamic therapy, gene therapy, phytochemicals, nanotheranostics, and CRISPR/Cas technology. These novel strategies offer promising avenues for improving the outcomes and quality of life for patients with OSCC. Ongoing research and clinical trials are essential to further refine these approaches and make them widely available.

Authors

Publication Details

Journal
Oral Sciences Reports
Published
2025-09-19
DOI
https://doi.org/10.12982/osr.2025.054
Primary Topic
RNA Interference and Gene Delivery
Type
article
Field-Weighted Citation Impact
0.00
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article

Novel Therapeutic Strategies for Oral Squamous Cell Carcinoma-An Overview

Madhu Narayan, V Vasanthi, Bose Divya, Asmita Kumari et al.
Oral Sciences Reports
RNA Interference and Gene Delivery
article

Novel Therapeutic Strategies for Oral Squamous Cell Carcinoma-An Overview

Madhu Narayan, V Vasanthi, Bose Divya, Asmita Kumari, K Rajkumar, S Mounika
article en

Abstract

Surgery, radiotherapy, and chemotherapy have been the mainstay of oral squamous cell carcinoma (OSCC) management. However, these treatments often come with significant side effects and limitations, including systemic toxicity and drug resistance. Recent advancements in therapeutic strategies for oral cancer have focused on more targeted and less invasive approaches. Some of the novel therapeutic strategies for OSCC include immunotherapy, targeted therapy, photodynamic therapy, gene therapy, phytochemicals, nanotheranostics, and CRISPR/Cas technology. These novel strategies offer promising avenues for improving the outcomes and quality of life for patients with OSCC. Ongoing research and clinical trials are essential to further refine these approaches and make them widely available.

Oral Sciences ReportsVol. 46(3)
Openalex Percentile: Top 77%
RNA Interference and Gene Delivery
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