Identification and therapeutic investigation of biomarker genes underpinning hepatocellular carcinoma: an in silico study utilising molecular docking and dynamics simulation
This study enhances our understanding of HCC biology and offers new insights into drug interactions. It presents several promising biomarkers for the early diagnosis, prognosis, and therapy. Further investigation into CDK1/CKS2 as a therapeutic target and the role of the identified biomarkers could contribute to improved diagnostic and therapeutic strategies for HCC.
Authors
- S Rehan Ahmad (ORCID: https://orcid.org/0000-0003-0796-5238)
- Chittabrata Mal (ORCID: https://orcid.org/0000-0001-5802-7474)
- Abdullah M. Alshahrani (ORCID: https://orcid.org/0000-0002-9188-4088)
- Md Abul Kalam (ORCID: https://orcid.org/0000-0003-4236-8519)
- Subhadip Das (ORCID: https://orcid.org/0000-0001-9030-9471)
- Devarshi Bhattacharyya (ORCID: https://orcid.org/0000-0003-1694-8106)
- Japita Ghosh (ORCID: https://orcid.org/0000-0002-5733-5173)
- Sunil Kanti Mondal
- Aritra Palodhi
Institutions
- University of Burdwan (IN)
- Government of West Bengal (IN)
- Maulana Abul Kalam Azad Institute of Asian Studies (IN)
- King Khalid University (SA)
- Maulana Abul Kalam Azad University of Technology, West Bengal (IN)
Publication Details
- Journal
- Frontiers in Bioinformatics
- Published
- 2025-09-19
- DOI
- https://doi.org/10.3389/fbinf.2025.1567748
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00