Impact of pregnant mothers’ previous COVID-19 infection and vaccination on newborns’ serological profiling
In our study, we found significantly higher titres of NTAb*3.31 and S-RBD*1.15 antibodies in newborns' cord blood whose mothers had previous COVID-19 infection or received COVID-19 vaccination; however, these titres were higher in the case of vaccination than previous infection. The more doses of vaccine received, the higher the antibody levels in newborns' cord blood. This indicates transplacental immunity transmission from mothers to their newborns after previous COVID-19 vaccination or infection.
Authors
- Gheyath K. Nasrallah (ORCID: https://orcid.org/0000-0001-9252-1038)
- Ratheesh Paramban
- Prem Chandra (ORCID: https://orcid.org/0000-0001-6922-7121)
- Ismail Sabry Abdelhady
- Mohammad A. A. Bayoumi (ORCID: https://orcid.org/0000-0002-2627-4806)
- Jim Abraham (ORCID: https://orcid.org/0000-0001-5038-1735)
- Alaa Masry
- Tawa Olukade (ORCID: https://orcid.org/0000-0002-2103-5355)
- Hana J Abukhadijah (ORCID: https://orcid.org/0009-0008-7993-7467)
- Mai AlQubaisi
- Nader Al‐Dewik (ORCID: https://orcid.org/0000-0001-5739-1135)
- Jacinth Joseph (ORCID: https://orcid.org/0000-0002-7932-0511)
- Anoop Sudarsanan
- S George
- Sheena Joy
- Mohammed Abugubba
- Yasser Al-Matar
- Maged Soliman Al-Shanwar
- Charity Sajor
- Sudheer Thazhe
Institutions
- Hamad Medical Corporation (QA)
- Qatar University (QA)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1526264
- Citations
- 1
- Primary Topic
- COVID-19 Impact on Reproduction
- Type
- article
- Field-Weighted Citation Impact
- 2.06
Funders
- Hamad Medical Corporation
- Qatar National Library
- Medical Research Council