A highly divergent sample from a nearly extinct SARS-CoV-2 lineage in a patient with long-term COVID-19
Our analysis adds to the growing body of evidence that the evolution of SARS-CoV-2 in chronically infected patients can be a major source of novel epidemiologically important variants and points to the potential role of the GI tract in long-term infection.
Authors
- Dmitry A. Lioznov (ORCID: https://orcid.org/0000-0003-3643-7354)
- Andrey B. Komissarov (ORCID: https://orcid.org/0000-0003-1733-1255)
- Thomas P. Peacock (ORCID: https://orcid.org/0000-0001-7077-2928)
- Elena Nabieva (ORCID: https://orcid.org/0000-0002-4532-6085)
- Kseniya Komissarova (ORCID: https://orcid.org/0000-0002-1465-5548)
- Cornelius Roemer (ORCID: https://orcid.org/0000-0002-6138-6539)
- Galya V. Klink (ORCID: https://orcid.org/0000-0001-8466-6958)
- Daria Danilenko (ORCID: https://orcid.org/0000-0001-6174-0836)
- Maria V. Sergeeva (ORCID: https://orcid.org/0000-0003-0411-9896)
- Maria Pisareva (ORCID: https://orcid.org/0000-0002-1499-9957)
- Georgii A. Bazykin (ORCID: https://orcid.org/0000-0003-2334-2751)
- A. A. Ivanova (ORCID: https://orcid.org/0000-0002-3495-4393)
- Ryan Hisner (ORCID: https://orcid.org/0000-0001-8296-9373)
- Federico Gueli
- Artem Fadeev (ORCID: https://orcid.org/0000-0003-3558-3261)
- Stanislav V. Zaitsev
- Kira Kudrya
Institutions
- National Research University Higher School of Economics (RU)
- SIB Swiss Institute of Bioinformatics (CH)
- University of Cape Town (ZA)
- University of Basel (CH)
- International University in Moscow (RU)
- Russian Engineering Academy (RU)
- NIHR Imperial Biomedical Research Centre (GB)
- Research Institute of Influenza (RU)
- Imperial College London (GB)
- Kaluga State University named after K.E.Tsiolkovski (RU)
- Russian Academy of Natural Sciences (RU)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-09-19
- DOI
- https://doi.org/10.3389/fcimb.2025.1623390
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research University Higher School of Economics