Bidirectional impact of dementia and aspiration pneumonia on cognitive decline in older adults: A retrospective cohort analysis
This study revealed that dementia severity substantially increases time-dependent pneumonia hazard (severe dementia HR = 3.01), while pneumonia accelerates cognitive deterioration, forming a bidirectional cycle amplified by swallowing dysfunction. Early dysphagia management and pneumonia prevention strategies are crucial for disrupting this progression in older adults. Geriatr Gerontol Int 2025; 25: 1481-1487.
Authors
- Yuquan Wu (ORCID: https://orcid.org/0000-0002-6934-7921)
- Jian Xu (ORCID: https://orcid.org/0000-0002-4227-2608)
- Jie Yan (ORCID: https://orcid.org/0000-0001-6877-5193)
- Wei Zheng (ORCID: https://orcid.org/0000-0003-1226-070X)
- Ran Meng (ORCID: https://orcid.org/0000-0003-1190-4710)
- Qingyong Chen
Institutions
- Anhui Medical University (CN)
- 117th Hospital of People's Liberation Army (CN)
Publication Details
- Journal
- Geriatrics and gerontology international/Geriatrics & gerontology international
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1111/ggi.70176
- Citations
- 2
- Primary Topic
- Dysphagia Assessment and Management
- Type
- article
- Field-Weighted Citation Impact
- 6.24