Molecular insights into carbapenemase-producing Enterobacterales from Senegal

This study highlights the spread of NDM-5 and OXA-181 in Senegal, and reports the first co-occurrence of NDM-5 and OXA-48 in sub-Saharan Africa. The spread of CPE, especially in high-risk clones, underscores the urgent need for continued surveillance and targeted interventions.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2025-08-27
DOI
https://doi.org/10.1093/jac/dkaf328
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
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article

Molecular insights into carbapenemase-producing Enterobacterales from Senegal

Issa Ndiaye, Delphine Girlich, Abdou Diop, Saoussen Oueslati et al.
Journal of Antimicrobial Chemotherapy
Antibiotic Resistance in Bacteria
article

Molecular insights into carbapenemase-producing Enterobacterales from Senegal

Issa Ndiaye, Delphine Girlich, Abdou Diop, Saoussen Oueslati, Bissoume Sambe, Thierry Naas, Laurent Dortet, Rémy A. Bonnin, Abdoulaye Cissé, Océane Vanparis, Babacar Ndiaye, Imene Mehidi, Ousmane Sow, Abdoulaye Seck, Adja Bousso Gueye, Alexis Proust, Elhadj Aly NIANG
article en

Abstract

This study highlights the spread of NDM-5 and OXA-181 in Senegal, and reports the first co-occurrence of NDM-5 and OXA-48 in sub-Saharan Africa. The spread of CPE, especially in high-risk clones, underscores the urgent need for continued surveillance and targeted interventions.

Journal of Antimicrobial ChemotherapyVol. 80(11)
Inserm (FR), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR), Université Paris-Saclay (FR), Assistance Publique – Hôpitaux de Paris (FR), CEA Paris-Saclay (FR), CNR de la Résistance aux Antibiotiques (FR), Institut Pasteur de Dakar (SN), World Health Organization Regional Office for Africa (CG), Bicêtre Hospital (FR), Cheikh Anta Diop University (SN)
Openalex Percentile: Top 80%
Antibiotic Resistance in Bacteria
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Molecular insights into carbapenemase-producing Enterobacterales from Senegal — Issa Ndiaye, Delphine Girlich, et al. · Journal of Antimicrobial Chemotherapy (2025) | TGRS Research Map | TGRS