A Synthetic Short-Chain Polyphosphate Complexed With Silica Nanoparticle, Corrects Coagulopathy Under Hemodilute, Hypothermic, or Acidotic Conditions as Assessed by <i>In Vitro</i> Coagulation Assays

The results demonstrate the potential of the polyP-SNP complex as a prohemostatic therapeutic for noncompressible hemorrhage, including under lethal triad conditions.

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Publication Details

Journal
Military Medicine
Published
2025-04-18
DOI
https://doi.org/10.1093/milmed/usaf176
Primary Topic
Trauma, Hemostasis, Coagulopathy, Resuscitation
Type
article
Field-Weighted Citation Impact
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article

A Synthetic Short-Chain Polyphosphate Complexed With Silica Nanoparticle, Corrects Coagulopathy Under Hemodilute, Hypothermic, or Acidotic Conditions as Assessed by In Vitro Coagulation Assays

Damien Kudela, Genmin Lu, B S Andrea Ashford-Hicks
Military Medicine
Trauma, Hemostasis, Coagulopathy, Resuscitation
article

A Synthetic Short-Chain Polyphosphate Complexed With Silica Nanoparticle, Corrects Coagulopathy Under Hemodilute, Hypothermic, or Acidotic Conditions as Assessed by In Vitro Coagulation Assays

Damien Kudela, Genmin Lu, B S Andrea Ashford-Hicks
article en

Abstract

The results demonstrate the potential of the polyP-SNP complex as a prohemostatic therapeutic for noncompressible hemorrhage, including under lethal triad conditions.

Military MedicineVol. 190(Supplement_2)
490 BioTech (United States) (US)
Openalex Percentile: Top 70%
Trauma, Hemostasis, Coagulopathy, Resuscitation
DOISourceOpenAlex
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A Synthetic Short-Chain Polyphosphate Complexed With Silica Nanoparticle, Corrects Coagulopathy Under Hemodilute, Hypothermic, or Acidotic Conditions as Assessed by <i>In Vitro</i> Coagulation Assays — Damien Kudela, Genmin Lu, et al. · Military Medicine (2025) | TGRS Research Map | TGRS