Vaccine Induced Seroreactivity Following Administration of ALVAC-HIV/AIDSVAX®B/E Identified by Common Anti-HIV Test Kits and Algorithms in Thailand
Vaccine-induced seroreactivity (VISR) was evaluated in RV306 and was shown to vary markedly (0-32.5%) among 6 HIV diagnostic tests and 84 algorithms. Our data show that selecting the SD Bioline HIV-1/2 assay and algorithms which exclude the ImmunoComb®II Bispot and Alere™ Determine HIV-1/2 assays would almost eliminate VISR in RV306.
Authors
- Faruk Sinangil
- Sanjay Gurunathan (ORCID: https://orcid.org/0009-0007-7241-6370)
- Jiraporn Puangkaew
- Surawach Rittiroongrad
- Bessara Nuntapinit
- Kittipong Rungruengthanakit
- Donald Francis
- Elisavet Serti (ORCID: https://orcid.org/0000-0003-4129-0254)
- Pornchanok Panjapornsuk
- Weerawan Chuenarom
- Boonlure Pruenglampoo
- Charla Andrews
- Piyathida Sroysuwan
- Nicos Karasavvas (ORCID: https://orcid.org/0000-0001-7372-4294)
- Suwat Chariyalertsak (ORCID: https://orcid.org/0000-0002-4998-7841)
- Jittima Dhitavat (ORCID: https://orcid.org/0000-0001-7346-7662)
- Kanlaya Wongworapat
- Nuntisa Chotirosniramit (ORCID: https://orcid.org/0000-0001-9066-4772)
- James Tartaglia
- Chirapa Eamsila
- Nelson L. Michael (ORCID: https://orcid.org/0000-0001-5882-5548)
- Phiromrat Rakyat
- Siriwat Akapirat (ORCID: https://orcid.org/0000-0001-6657-0960)
- Chitraporn Karnasuta
- Pawinee Jarujareet
- Jean‐Louis Excler (ORCID: https://orcid.org/0000-0002-6462-5101)
- Leigh Anne Eller (ORCID: https://orcid.org/0000-0003-2043-1513)
- Sirinan Madnote
- Nittaya Phanuphak (ORCID: https://orcid.org/0000-0002-0036-3165)
- Hathairat Savadsuk
- Supat Chamnanchanunt (ORCID: https://orcid.org/0000-0001-9916-327X)
- Nitiya Chomchey (ORCID: https://orcid.org/0000-0002-0539-4542)
- Kessuda Khowsroy
- James L. K. Fletcher (ORCID: https://orcid.org/0000-0001-7894-2098)
- Punnee Pitisuttithum (ORCID: https://orcid.org/0000-0003-3215-2183)
- Thep Chalermchai (ORCID: https://orcid.org/0000-0001-7839-7835)
- Patcharaphan Sugandhavesa
- Oranitcha Kaewthip
- Chiaka Nwoga (ORCID: https://orcid.org/0000-0002-4514-330X)
- Trevor A. Crowell (ORCID: https://orcid.org/0000-0001-5947-265X)
- Jaranit Kaewkungwal (ORCID: https://orcid.org/0000-0001-7916-8460)
- Punnee Pitisutthithum
- Taweewat Supindham
- Rapee Trichavaroj (ORCID: https://orcid.org/0000-0003-0139-8674)
- Eugène Kroon (ORCID: https://orcid.org/0000-0002-8235-7155)
- Tanyaporn Wansom (ORCID: https://orcid.org/0000-0002-0087-3341)
- Nongluck Sangnoi
- Anant Phramtong
- Sorachai Nitayaphan (ORCID: https://orcid.org/0000-0001-6935-1405)
- Prapaporn Savaraj
- Nipat Teeratakulpisarn
- Carter Lee (ORCID: https://orcid.org/0000-0001-9118-106X)
- Merlin L. Robb (ORCID: https://orcid.org/0000-0003-3949-9649)
- Siriluck Teerachia
- Praphan Phanuphak (ORCID: https://orcid.org/0000-0002-8669-1847)
- Elizabeth Heger
- Nampueng Churikanont
- Narongrid Sirisopana
- Surat Jongrakthaitae
- Alexandra Schuetz (ORCID: https://orcid.org/0000-0003-2829-1340)
- Jintanat Ananworanich
- Kirsten Smith
- Natthapol Kosashunhanan (ORCID: https://orcid.org/0000-0002-5273-4976)
- Jerome H. Kim
- Sanjay Phogat
- Bhubate Tongchanakarn
- Jittima Dhitavat Benjaluck Phonrat
- Arom Pitisuttithum
- Wanlaya Lapwech
- Wathee Sithi
- Bhubate Tongchanakarn Hathairat Savadsuk
- Kittimasak Hunprasert Yuwadee Puangngern
- Pornsuk Visudhiphan Saowanit Getchalarat
- Anocha Kleebmontha
Institutions
- Henry M. Jackson Foundation (US)
- Mahidol University (TH)
- Sanofi (United States) (US)
- Armed Forces Research Institute of Medical Science (TH)
- Mahidol Oxford Tropical Medicine Research Unit (TH)
- Global Solutions for Infectious Diseases (US)
- Chiang Mai University (TH)
- Walter Reed Army Institute of Research (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-09-15
- DOI
- https://doi.org/10.1093/ofid/ofaf578
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00