Development of a smartphone-based app to support the differential diagnosis in patients with primary left ventricular hypertrophy
The Thick-Heart App correctly classified 93% of cases into the most-likely diagnosis category (sensitivity 88-100%, specificity 97%). Our study underscores the potential clinical value of digital decision support tools to enable timelier identification of specific cardiomyopathies, by promoting awareness in non-reference settings.
Authors
- Perry Elliott (ORCID: https://orcid.org/0000-0003-3383-3984)
- Ioannis Kachrimanidis (ORCID: https://orcid.org/0009-0006-8964-329X)
- Ioannis Skalidis (ORCID: https://orcid.org/0000-0002-4374-0389)
- Francesca Girolami (ORCID: https://orcid.org/0000-0001-9143-3597)
- Emanuele Monda (ORCID: https://orcid.org/0000-0001-9304-988X)
- Ella Field (ORCID: https://orcid.org/0000-0002-0808-2763)
- Iacopo Olivotto (ORCID: https://orcid.org/0000-0003-1751-9266)
- Juan Pablo Kaski (ORCID: https://orcid.org/0000-0002-0014-9927)
- Giuseppe Limongelli (ORCID: https://orcid.org/0000-0002-8291-9517)
- Maurizio Pieroni (ORCID: https://orcid.org/0000-0002-6830-4292)
- Panagiotis Antiochos (ORCID: https://orcid.org/0000-0001-8466-7360)
- Niccolò Maurizi (ORCID: https://orcid.org/0000-0001-5819-204X)
- Silvia Passantino
- Henri Lu (ORCID: https://orcid.org/0000-0002-9074-6505)
- Elena Biagini (ORCID: https://orcid.org/0000-0003-0295-0440)
- Alessia Argirò (ORCID: https://orcid.org/0000-0002-6394-9948)
- Carlo Fumagalli (ORCID: https://orcid.org/0000-0001-7963-5049)
- Franco Cecchi (ORCID: https://orcid.org/0000-0002-2035-5621)
- Francesco Cappelli (ORCID: https://orcid.org/0000-0001-7237-1714)
- Gabriella Dallaglio (ORCID: https://orcid.org/0009-0001-0487-2397)
Institutions
- St Bartholomew's Hospital (GB)
- Cardiovascular Institute of the South (US)
- Great Ormond Street Hospital (GB)
- Centre Hospitalier Universitaire Vaudois (CH)
- Meyer Children's Hospital (IL)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Ippokrateio General Hospital of Thessaloniki (GR)
- Azienda USL di Bologna (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Associazione Italiana Vulvodinia Onlus (IT)
- Institut Cardiovasculaire Paris Sud (FR)
- University College London (GB)
- University of Lausanne (CH)
Publication Details
- Journal
- European Heart Journal - Digital Health
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1093/ehjdh/ztaf105
- Primary Topic
- Mobile Health and mHealth Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amicus Therapeutics