Modification of the Dispersion Curve Shape of Liver Tissue Conductivity under the Influence of Destructive Factors

This work investigates the frequency dispersion of electrical properties of biological tissues, particularly pig liver, using spectral analysis of conductivity. Numerical differentiation of impedance characteristics was applied over a wide frequency range (0.01 Hz – 100 kHz) to identify local transitions between tissue electrophysiological regimes. It is shown that the position of the local minimum of the first derivative of the imaginary part of specific conductivity near 1 Hz, corresponding to alpha-dispersion and interfacial polarization on cell membranes, remains stable regardless of sample size but shifts sensitively under the influence of destructive factors (e.g., temperature, radiation). These results confirm the feasibility of using conductivity derivatives as an informative marker of structural changes in tissues, complementing classic impedance approaches for diagnosing and monitoring pathological processes.