Serum Minerals and Male Age-related Hypogonadism: Multimodal Evidence Decoding Associations and Intervention Strategies
Serum iron bidirectionally modulates testicular function through redox and metabolic networks. Our findings establish age as an effect modifier in mineral-endocrine interactions, emphasize personalized precision nutrition strategies, and uncover novel bilirubin-mediated regulatory pathways.
Authors
- Junfeng Xie
- Ke Wang (ORCID: https://orcid.org/0000-0002-5845-7228)
- Jiaxi Yao (ORCID: https://orcid.org/0000-0002-8023-4338)
- Wenqiang Cao (ORCID: https://orcid.org/0000-0002-5024-0817)
- Z. Y. Hu (ORCID: https://orcid.org/0000-0003-0920-6219)
- Chengyuan Wang (ORCID: https://orcid.org/0000-0001-9789-508X)
- Tao Liu (ORCID: https://orcid.org/0000-0002-3044-8813)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- First Hospital of China Medical University (CN)
- Chongqing Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1210/clinem/dgaf501
- Primary Topic
- Iron Metabolism and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00