Predictors of Post-Alteplase Long-Term Unfavorable Outcome in Atrial Fibrillation Patients Presented with Embolic Stroke in the Middle East and North Africa Regions: A Multi-center, Longitudinal Study

Higher baseline NIHSS, heart failure, post-thrombolysis intracranial haemorrhage, and recurrent symptomatic stroke were independent predictors of long-term post-thrombolysis unfavorable functional outcome in embolic stroke patients. Novelly, higher HAS-BLED and CHA2DS2-VASc scores were independent predictors of long-term post-thrombolysis unfavorable functional outcome in Arabian patients. Moreover, sustained AF was an independent predictor of long-term post-thrombolysis unfavorable functional outcome.

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Publication Details

Journal
Neurology and Therapy
Published
2025-09-19
DOI
https://doi.org/10.1007/s40120-025-00814-x
Citations
6
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
8.13
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article

Predictors of Post-Alteplase Long-Term Unfavorable Outcome in Atrial Fibrillation Patients Presented with Embolic Stroke in the Middle East and North Africa Regions: A Multi-center, Longitudinal Study

Abdalazeem Ibrahem, Salah Ibrahim Ahmed, Sherihan Rezk Ahmed, Shady S. Georgy et al.
6 citations
Neurology and Therapy
Acute Ischemic Stroke Management
8.13
article

Predictors of Post-Alteplase Long-Term Unfavorable Outcome in Atrial Fibrillation Patients Presented with Embolic Stroke in the Middle East and North Africa Regions: A Multi-center, Longitudinal Study

Abdalazeem Ibrahem, Salah Ibrahim Ahmed, Sherihan Rezk Ahmed, Shady S. Georgy, Ahmed Zaki Omar Akl, Mohamed G. Zeinhom, Hesham Eissa, Youssry Salah Shafiq Kerolos, Essam E. Khalil, Mohamed Ismaiel, Ahmed Ahmed Mohamed Kamal Ebied, Hossam Mohamed Refat, Mohamed Fouad Elsayed Khalil, Emad Labib Abdelhamid Mahmoud, Mohamed Elshafei, Amir Ahmed Elsaeed Egila, Ahmad Galal Mohammed Mohammed Elmesallami, Tamer Shaaban Zedan, Karam Dahy Hamdan Hassaneen
article en
6 citations

Abstract

Higher baseline NIHSS, heart failure, post-thrombolysis intracranial haemorrhage, and recurrent symptomatic stroke were independent predictors of long-term post-thrombolysis unfavorable functional outcome in embolic stroke patients. Novelly, higher HAS-BLED and CHA2DS2-VASc scores were independent predictors of long-term post-thrombolysis unfavorable functional outcome in Arabian patients. Moreover, sustained AF was an independent predictor of long-term post-thrombolysis unfavorable functional outcome.

Neurology and TherapyVol. 14(6)
Ain Shams University (EG), Kafrelsheikh University (EG), Al Noor Hospitals (AE), Cairo University (EG), Al-Azhar University (EG), Zagazig University (EG), Latifa Hospital (AE), Shaikh Zayed Hospital (PK), Dubai Hospital (AE), GMC Hospital (AE), Khoula Hospital (OM), Security Forces Hospital (SA), King Fahad Hospital Jeddah (SA), Islamic University of Madinah (SA), Shebin Teaching Hospital (EG), Ajman Specialty General Hospital (AE)
Openalex Percentile: Top 2%
Acute Ischemic Stroke Management
8.13
DOIOpen Access PDFOpenAlex
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