Risk and protective factors for postoperative anastomotic leakage in esophageal and gastrointestinal surgery: an umbrella review of meta-analyses and systematic reviews
AL remains a major challenge in gastrointestinal surgery, and involves multiple risk factors. Optimizing perioperative management, refining intraoperative techniques, and judicious use of antibiotics and NSAIDs can significantly reduce the risk of AL. Future research should focus on high-quality, large-sample, multicenter studies to explore more effective prevention and treatment strategies.
Authors
- Song Cao (ORCID: https://orcid.org/0000-0002-3231-6136)
- Ke-Qian Yi
- Xinhua Bao (ORCID: https://orcid.org/0000-0003-3670-159X)
- Pengwei Su
- Yang Shen (ORCID: https://orcid.org/0000-0002-1077-7273)
- JI-BIN CHENG
- Yijun Li (ORCID: https://orcid.org/0000-0002-7251-2000)
- Xingzhi Wang (ORCID: https://orcid.org/0000-0003-0771-3903)
- Biao Hu (ORCID: https://orcid.org/0000-0003-4753-9583)
- Pengyuan Xu
- Qingwen Xu (ORCID: https://orcid.org/0000-0002-4796-3141)
Institutions
- Kunming Medical University (CN)
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1097/js9.0000000000003308
- Citations
- 1
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01