Investigation of clinical and genetic characteristics of Alport syndrome using a national registry in Japan (JP-ALPS)
In our cohort, which consisted mainly of patients who did not require kidney replacement therapy in childhood and adolescence, kidney function was preserved throughout this period except for some male patients with X-linked Alport syndrome. RAS inhibitor use may be associated with a reduced rate of eGFR decline.
Authors
- Masao Ogura
- Naoya Fujita (ORCID: https://orcid.org/0000-0002-9631-9264)
- Kei Nishiyama (ORCID: https://orcid.org/0000-0003-3676-0135)
- Kandai Nozu (ORCID: https://orcid.org/0000-0002-0290-3137)
- Riku Hamada (ORCID: https://orcid.org/0000-0002-7151-459X)
- Kenichiro Miura (ORCID: https://orcid.org/0000-0002-9483-8482)
- Naoko Ito (ORCID: https://orcid.org/0009-0009-2536-6571)
- Takayuki Okamoto (ORCID: https://orcid.org/0000-0002-6029-451X)
- Tetsuji Inagaki
- Koichi Nakanishi (ORCID: https://orcid.org/0000-0001-8681-9129)
- Tomohiko Yamamura (ORCID: https://orcid.org/0000-0001-6107-1169)
- Ryota Suzuki (ORCID: https://orcid.org/0009-0000-2005-8603)
- Yuko Shima (ORCID: https://orcid.org/0000-0003-3944-0110)
- Hiroyasu Tsukaguchi
- Yoko Shirai (ORCID: https://orcid.org/0000-0003-3734-4766)
- Shunsuke Shinozuka
- Masafumi Oka
- Yusuke Okuda (ORCID: https://orcid.org/0000-0003-3707-695X)
- Kiyonobu Ishizuka (ORCID: https://orcid.org/0000-0003-1162-6714)
- Naoaki Mikami
- Chikako Terano (ORCID: https://orcid.org/0000-0002-7816-7455)
- Wataru Shimabukuro (ORCID: https://orcid.org/0000-0002-2828-4530)
- Hiroshi Hataya (ORCID: https://orcid.org/0000-0003-0241-6467)
- Kenji Ishikura (ORCID: https://orcid.org/0000-0003-2692-6437)
- Tomoko Horinouchi (ORCID: https://orcid.org/0000-0003-1655-6030)
- Koichi Kamei (ORCID: https://orcid.org/0000-0003-3528-6961)
- Kazuki Tanaka (ORCID: https://orcid.org/0000-0002-9766-0157)
- Taeko Hashimoto
Institutions
- Kansai Medical University (JP)
- Kyushu University (JP)
- Saga University (JP)
- Wakayama Medical University (JP)
- Hokkaido University (JP)
- University of the Ryukyus (JP)
- Miyagi Children's Hospital (JP)
- Kasugai Municipal Hospital (JP)
- Matsudo City Hospital (JP)
- National Center For Child Health and Development (JP)
- Tokyo Women's Medical University (JP)
- Tokyo Metropolitan Children's Medical Center (JP)
- University of the Ryukyus University Hospital (JP)
- Kitasato University (JP)
- Kobe University (JP)
Publication Details
- Journal
- Clinical and Experimental Nephrology
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1007/s10157-025-02758-w
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Teikyo University School of Medicine
- Dokkyo Medical University
- University of Tokushima
- Nara Medical University
- Fujita Health University
- Saitama Medical University