Global burden of cirrhosis and other chronic liver diseases caused by specific etiologies from 1990 to 2021
Cirrhosis and chronic liver diseases remain a major global health challenge. NAFLD has emerged as the predominant cause of incident cirrhosis, affecting both high-income and lower-SDI countries, signaling a critical shift toward metabolic etiologies. These findings call for urgent, region-specific strategies that integrate prevention, early detection, and management of both infectious and metabolic liver disease risk factors.
Authors
- Yingzi Ming (ORCID: https://orcid.org/0000-0002-3004-4405)
- Ming Luo (ORCID: https://orcid.org/0000-0002-0762-6175)
- Ying Zhang (ORCID: https://orcid.org/0000-0001-9900-7568)
Institutions
- Central South University (CN)
- Wuhan University (CN)
- Hunan Provincial Center for Disease Control and Prevention (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Education Department of Hunan Province (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1186/s12876-025-04264-5
- Citations
- 7
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 9.48
Funders
- Hunan Provincial Science and Technology Department