Ribosome affinity carbon dots for live-cell imaging of endoplasmic reticulum
A strategy was designed to achieve ER fluorescence delivery by employing ribosomes as intracellular carriers. Levofloxacin, which has low toxicity to eukaryotic cells, was selected as the ribosome anchoring moiety and did not alter ribosome function. Surface-modified levofloxacin LT-CDs were synthesized for active targeting of the ER in the process of cell translation.
Authors
- Jin‐Xuan Fan (ORCID: https://orcid.org/0000-0002-8434-7591)
- Yuan‐Di Zhao (ORCID: https://orcid.org/0000-0002-4286-4275)
- Yong Li (ORCID: https://orcid.org/0000-0001-7971-4871)
- Kai Cheng (ORCID: https://orcid.org/0000-0001-9572-9360)
- Dong Zhou (ORCID: https://orcid.org/0000-0002-6565-0421)
- Fang Tan (ORCID: https://orcid.org/0000-0003-4115-8456)
- Jia-Hua Zou
Institutions
- Huanggang Normal University (CN)
- Jianghan University (CN)
- Wuhan National Laboratory for Optoelectronics (CN)
- Huanggang Central Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc04057d
- Primary Topic
- Carbon and Quantum Dots Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00