Real-World 24-Month Outcomes of Ofatumumab in Relapsing Multiple Sclerosis: Efficacy, Safety, and the Impact of Frailty
This real-world study suggests that OFA is effective and safe for MS, offering rapid disease control. Lower frailty levels suggest preferential use in patients with lower baseline disability. Further large-scale, long-term studies are needed.
Authors
- Roberta Fantozzi (ORCID: https://orcid.org/0000-0002-7527-575X)
- Francesca Napoli (ORCID: https://orcid.org/0000-0002-9745-998X)
- Daniele Belvisi
- Carla Tortorella (ORCID: https://orcid.org/0000-0001-9037-7300)
- Shalom Haggiag (ORCID: https://orcid.org/0000-0002-5569-4121)
- Fabrizia Monteleone
- Elena Barbuti (ORCID: https://orcid.org/0000-0002-0450-7699)
- Antonella Conte (ORCID: https://orcid.org/0000-0002-6338-2961)
- Massimiliano Mirabella (ORCID: https://orcid.org/0000-0002-7783-114X)
- Fabiana Marinelli (ORCID: https://orcid.org/0000-0003-4697-2051)
- Marta Altieri (ORCID: https://orcid.org/0000-0003-3110-5932)
- Francesco Sica (ORCID: https://orcid.org/0000-0002-7255-952X)
- Doriana Landi (ORCID: https://orcid.org/0000-0002-3309-8417)
- Valeria Pozzilli (ORCID: https://orcid.org/0000-0002-0556-0176)
- Diego Centonze (ORCID: https://orcid.org/0000-0001-8025-311X)
- Leonardo Malimpensa (ORCID: https://orcid.org/0000-0002-0945-4282)
- Maria Chiara Buscarinu (ORCID: https://orcid.org/0000-0002-4839-1528)
- Elisabetta Ferraro (ORCID: https://orcid.org/0000-0002-9596-4624)
- Giorgio Leodori (ORCID: https://orcid.org/0000-0002-6631-6740)
- Gina Ferrazzano (ORCID: https://orcid.org/0000-0002-6860-1182)
- Francesca Marchione
- Anna Chiara Landi
- Alessandra Cicia (ORCID: https://orcid.org/0000-0003-4356-3201)
- Giovanna Borriello (ORCID: https://orcid.org/0000-0001-6825-3889)
- Carlo Pozzilli (ORCID: https://orcid.org/0000-0002-6360-4798)
- Assunta Bianco (ORCID: https://orcid.org/0000-0002-7101-0949)
- Antonio Cortese (ORCID: https://orcid.org/0000-0002-0875-0725)
- Fabio Buttari (ORCID: https://orcid.org/0000-0002-6089-4670)
- M. Salvetti
- Girolama Alessandra Marfia
- Nicola Falcone
Institutions
- University of Rome Tor Vergata (IT)
- Università Campus Bio-Medico (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituto Neurologico Mediterraneo (IT)
- Accademia di Belle Arti di Frosinone (IT)
- Ellis Hospital (US)
- Ospedale San Filippo Neri (IT)
- CTO Andrea Alesini (IT)
- Federico II University Hospital (IT)
- Ospedale di Belcolle (IT)
- Ospedale Santa Maria Goretti (IT)
- Carlo Forlanini Hospital (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Neurology and Therapy
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1007/s40120-025-00818-7
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94