Endovascular Thrombectomy Versus Best Medical Therapy for Large Vessel Occlusion Stroke Beyond 24 Hours: A Systematic Review and Meta-Analysis
Our results revealed that EVT was associated with improved functional outcomes without an increase in 90-day mortality, despite a higher symptomatic intracranial hemorrhage risk. Given the limited CoE and overall study quality, ongoing randomized trials are essential to confirm these findings and guide patient selection in the ultra-late time window.
Authors
- Dileep R. Yavagal (ORCID: https://orcid.org/0000-0003-4739-0133)
- Santiago Ortega‐Gutiérrez (ORCID: https://orcid.org/0000-0002-3408-1297)
- Cristian Morán‐Mariños (ORCID: https://orcid.org/0000-0002-1353-0540)
- Martha I. Vilca-Salas (ORCID: https://orcid.org/0000-0001-8349-7216)
- Nagheli Fernanda Borjas‐Calderón (ORCID: https://orcid.org/0000-0001-6078-9523)
- Fabian A. Chavez‐Ecos (ORCID: https://orcid.org/0000-0001-5637-2397)
- Negar Asdaghi (ORCID: https://orcid.org/0000-0002-0285-825X)
- Sai Sanikommu (ORCID: https://orcid.org/0009-0006-3637-5033)
- Aarón Rodríguez-Calienes (ORCID: https://orcid.org/0000-0002-8413-6954)
- Pedro Bartkevitch Rodrigues (ORCID: https://orcid.org/0009-0004-3716-5201)
Institutions
- University of Miami (US)
- Universidad Peruana Cayetano Heredia (PE)
- Universidad de San Martín de Porres (PE)
- Universidad Científica del Sur (PE)
- Universidad San Ignacio de Loyola (PE)
- University of Iowa Hospitals and Clinics (US)
- Jackson Memorial Hospital (US)
- Saint Aloysius Gonzaga National University (PE)
Publication Details
- Journal
- Stroke
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1161/strokeaha.125.052121
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35