Prevalence and Antibiotic Resistance Patterns of Escherichia coli in Clinical Samples from Patients in Anyigba, Kogi State, Nigeria

This study aimed to investigate the prevalence of Escherichia coli in clinical samples collected from patients in Anyigba, Kogi State, Nigeria, and to determine the antibiotic resistance patterns of the isolated strains. A total of 200 clinical samples were analyzed, including urine, stool, and blood samples. Escherichia coli was identified in 70 of the 200 samples (35%), with the highest prevalence observed in urine samples (45%). Antibiotic susceptibility testing revealed high resistance rates to ampicillin (80%), tetracycline (60%), and ciprofloxacin (30%), while lower resistance rates were observed for nitrofurantoin (21%) and ceftriaxone (14%). The findings of this study highlight the significant burden of Escherichia coli infections in Anyigba and the urgent need for effective antibiotic stewardship measures to address the rising issue of antibiotic resistance. Further research is necessary to understand the factors contributing to the high prevalence of Escherichia coli in this region and to develop targeted interventions to improve public health.