Randomised, controlled Trial of CT perfusion and angiography compared to CT alone in thrombolysis-eligible acute ischaemic stroke patients: The penumbra and recanalisation acute computed tomography in ischaemic stroke evaluation (PRACTISE) trial
Among acute stroke patients imaged <4.5 h from symptom onset, multimodal CT reduced use of thrombolysis. Treatment decision times and clinical outcomes did not differ between groups.
Authors
- Joanna Marguerite Wardlaw (ORCID: https://orcid.org/0000-0002-9812-6642)
- Grant Mair (ORCID: https://orcid.org/0000-0003-2189-443X)
- Ian Ford (ORCID: https://orcid.org/0000-0001-5927-1823)
- Phil White (ORCID: https://orcid.org/0000-0001-6007-6013)
- L. Sztriha (ORCID: https://orcid.org/0000-0003-4639-3180)
- Omid Halse (ORCID: https://orcid.org/0000-0003-0202-0083)
- Sanjeev Nayak (ORCID: https://orcid.org/0000-0003-4156-5000)
- Keith W. Muir (ORCID: https://orcid.org/0000-0001-9535-022X)
- Ibrahim Balogun (ORCID: https://orcid.org/0000-0001-8078-5378)
- Salwa El Tawil (ORCID: https://orcid.org/0000-0002-0473-8091)
- Elizabeth A. Warburton (ORCID: https://orcid.org/0000-0003-2575-3255)
- Kausik Chatterjee
- Alex McConnachie (ORCID: https://orcid.org/0000-0002-7262-7000)
- Jattinder Khaira
Institutions
- University of Liverpool (GB)
- University of Cambridge (GB)
- Royal Stoke University Hospital (GB)
- Charing Cross Hospital (GB)
- Kent and Canterbury Hospital (GB)
- UK Dementia Research Institute (GB)
- Countess of Chester Hospital (GB)
- NIHR Surgical Reconstruction and Microbiology Research Centre (GB)
- King's College Hospital (GB)
- Queen Elizabeth University Hospital (GB)
- University of Glasgow (GB)
- Newcastle University (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- European Stroke Journal
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1177/23969873251372348
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35