Light-triggered quenching of the <sup>19</sup> F-MRI signal from micelle-encapsulated PERFECTA
We report the development of a fluorinated micellar nanosystem whose <sup>19</sup>F-MRI signal can be selectively dimmed by application of an external stimulus. A photo-activatable quencher unit (ferrocene) was co-encapsulated with the superfluorinated PERFECTA probe in colloidal micelles. While pristine micelles were MRI responsive ("On" state), their irradiation by light triggered the "Off" MRI-state of PERFECTA.
Authors
- Erwan Selingue (ORCID: https://orcid.org/0000-0002-8364-8659)
- Mélissa Glatigny
- Sébastien Mériaux (ORCID: https://orcid.org/0000-0001-7430-8348)
- Claire Leterrier
- Guillaume Pinna (ORCID: https://orcid.org/0000-0001-7841-7250)
- Eric Doris (ORCID: https://orcid.org/0000-0003-1318-602X)
- Edmond Gravel (ORCID: https://orcid.org/0000-0001-6077-1016)
- Françoise Geffroy (ORCID: https://orcid.org/0000-0001-9281-0972)
- Marie Vandamme
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université Paris Cité (FR)
- Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR)
- Université Paris-Saclay (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- CEA Paris-Saclay - Etablissement de Fontenay-aux-roses (FR)
- CEA Paris-Saclay (FR)
Publication Details
- Journal
- Nanoscale Horizons
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nh00468c
- Citations
- 1
- Primary Topic
- Lanthanide and Transition Metal Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.52