Therapeutic Drug Monitoring Versus Fixed-Interval Dosing of Dalbavancin in Implant-Associated Spinal Infections: Grand Round/A Case Study
TDM-guided dalbavancin therapy optimized drug exposure and reduced the number of doses compared with fixed-interval dosing, highlighting its potential to optimize treatment. Further research is required to establish standardized therapeutic drug monitoring protocols for the management of IASI.
Authors
- Aurelia H. M. de Vries Schultink (ORCID: https://orcid.org/0000-0003-0960-062X)
- Daan J. Touw (ORCID: https://orcid.org/0000-0002-1429-4789)
- Valentijn A. Schweitzer (ORCID: https://orcid.org/0000-0001-9640-7291)
- Tim Bognàr (ORCID: https://orcid.org/0000-0002-2429-8994)
- Jeroen P. A. Houwen (ORCID: https://orcid.org/0000-0001-5521-2519)
- Martha L. Toren-Wielema
- Charlotte S. Hakkers (ORCID: https://orcid.org/0000-0002-0164-7282)
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- Wilhelmina Children's Hospital (NL)
Publication Details
- Journal
- Therapeutic Drug Monitoring
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1097/ftd.0000000000001386
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00