Autoimmune Haemolytic Anaemia: A report of two cases with varied clinical course managed at the Kenyatta National Hospital, Nairobi, Kenya
Autoimmune Haemolytic Anaemia (AIHA) is a rare yet serious condition characterized by immune-mediated red cell destruction. It presents with anaemia, jaundice, and splenomegaly, requiring a high index of suspicion for timely diagnosis. We present two cases managed at the Kenyatta National Hospital (KNH), highlighting varied disease courses and treatment responses. Management includes corticosteroids as first-line therapy, with immunosuppressants or biologics like rituximab for refractory cases. Limited access to diagnostic tests and treatment options remains a challenge in Kenya. Addressing these barriers through improved clinician awareness and healthcare infrastructure is crucial for optimizing AIHA outcomes in resource-limited settings.
Authors
- Matilda Ong’ondi (ORCID: https://orcid.org/0000-0002-8386-4802)
- Debbie Mwende Mutua
Publication Details
- Journal
- Journal of Kenya Assocation of Physicians
- Published
- 2025-09-16
- DOI
- https://doi.org/10.4314/jkap.v7i2.5
- Primary Topic
- Blood groups and transfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00