Risk Factors for Endoscopic Gastric Mucosal Lesions: Analysis of Lifestyle, Dietary, and Clinical Determinants in 361 Patients

Current smoking showed a trend toward increased severity of gastric lesions in this Romanian cohort, though not reaching statistical significance. NSAID use was the only significant independent predictor. The dose-response relationship between cumulative risk factors and the severity of lesions emphasizes the importance of comprehensive risk assessment and multi-factorial interventions in gastric disease prevention. However, as a cross-sectional study, these associations cannot establish causality and should be confirmed in prospective cohorts.

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Publication Details

Journal
Life
Published
2025-09-19
DOI
https://doi.org/10.3390/life15091474
Primary Topic
Helicobacter pylori-related gastroenterology studies
Type
article
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article

Risk Factors for Endoscopic Gastric Mucosal Lesions: Analysis of Lifestyle, Dietary, and Clinical Determinants in 361 Patients

Anca Elena Negovan, Monica Pantea, Sabrina-Nicoleta Munteanu, Ana-Maria Filip et al.
Life
Helicobacter pylori-related gastroenterology studies
article

Risk Factors for Endoscopic Gastric Mucosal Lesions: Analysis of Lifestyle, Dietary, and Clinical Determinants in 361 Patients

Anca Elena Negovan, Monica Pantea, Sabrina-Nicoleta Munteanu, Ana-Maria Filip, Simona Liliana Mocan, Cristian-Ioan Cîmpian, Patrick-Lazăr-Dominik Chiciudean
article en

Abstract

Current smoking showed a trend toward increased severity of gastric lesions in this Romanian cohort, though not reaching statistical significance. NSAID use was the only significant independent predictor. The dose-response relationship between cumulative risk factors and the severity of lesions emphasizes the importance of comprehensive risk assessment and multi-factorial interventions in gastric disease prevention. However, as a cross-sectional study, these associations cannot establish causality and should be confirmed in prospective cohorts.

LifeVol. 15(9)
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș (RO), Spitalul Clinic Judetean de Urgenta Târgu Mureş (RO), Spitalul Clinic Judetean Mures (RO)
Openalex Percentile: Top 59%
Helicobacter pylori-related gastroenterology studies
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