Overlap Syndrome (Localized Scleroderma and Discoid Lupus Erythematosus) in a Child: Case Study

Background. The combination of systemic scleroderma and systemic lupus erythematosus is described sufficiently detailed in the literature. However, overlap of localized forms of scleroderma and discoid lupus erythematosus in children is described only in single clinical observations. Case description. Rare case study of overlap syndrome is presented, the results of drug treatment are demonstrated, differential diagnosis issues and disease pathogenetic features are highlighted. Conclusion. Diagnosis of overlap syndromes presents significant difficulties. Its untimely verification leads to ineffective management. As a result, persistent functional and cosmetic skin defects develop, leading to negative impact on patients' quality of life.

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Journal
Вопросы современной педиатрии
Published
2025-09-18
DOI
https://doi.org/10.15690/vsp.v24i4.2935
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Overlap Syndrome (Localized Scleroderma and Discoid Lupus Erythematosus) in a Child: Case Study

М. А. Леонова, Roman A. Ivanov, O.R. Katunina, Nikolay N. Murashkin et al.
Вопросы современной педиатрии
Systemic Sclerosis and Related Diseases
article

Overlap Syndrome (Localized Scleroderma and Discoid Lupus Erythematosus) in a Child: Case Study

М. А. Леонова, Roman A. Ivanov, O.R. Katunina, Nikolay N. Murashkin, Alexander I. Materikin, Кirill A. Kulikov, Leonid A. Opryatin, Ekaterina S. Pavlova, Roman V. Epishev, Yaroslav Yu. Alshevskiy
article en

Abstract

Background. The combination of systemic scleroderma and systemic lupus erythematosus is described sufficiently detailed in the literature. However, overlap of localized forms of scleroderma and discoid lupus erythematosus in children is described only in single clinical observations. Case description. Rare case study of overlap syndrome is presented, the results of drug treatment are demonstrated, differential diagnosis issues and disease pathogenetic features are highlighted. Conclusion. Diagnosis of overlap syndromes presents significant difficulties. Its untimely verification leads to ineffective management. As a result, persistent functional and cosmetic skin defects develop, leading to negative impact on patients' quality of life.

Вопросы современной педиатрииVol. 24(4)
Center for Children (US), Central State Medical Academy (RU)
Openalex Percentile: Top 64%
Systemic Sclerosis and Related Diseases
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Overlap Syndrome (Localized Scleroderma and Discoid Lupus Erythematosus) in a Child: Case Study — М. А. Леонова, Roman A. Ivanov, et al. · Вопросы современной педиатрии (2025) | TGRS Research Map | TGRS