Comment: Survival after risk-reducing mastectomy in young BRCA1 carriers with breast cancer
Women with breast cancer and a BRCA1 or BRCA2 mutation face high risks of contralateral breast cancer, and many opt for bilateral mastectomy. We used a simulation approach to predict the benefit of risk-reducing mastectomy (RRM) on 20-year survival.
Authors
- Vasily Giannakeas (ORCID: https://orcid.org/0000-0003-2924-8723)
- Steven A Narod
Institutions
- University of Toronto (CA)
- Women's College Hospital (CA)
- Public Health Ontario (CA)
Publication Details
- Journal
- BJC Reports
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1038/s44276-025-00180-z
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00