N-Methylcantharidimede：Synthesis and Anti-Hepatoma activity

N-methylcantharidimede (3) was synthesized by two different methods. The structure was confirmed by 1H NMR, 13C NMR and HRMS. The anti-hepatoma activities in vitro of the synthesized compounds were evaluated against HepG2 cell by the MTS assay. The biological results demonstrated that compounds 1, 4 showed good anti-hepatoma activity and 2, 3 showed rarely anti-hepatoma activity.

Authors

X Qiao
Xiaoling Liu (ORCID: https://orcid.org/0000-0002-9202-5015)
Zhi-Yi He
Chunbin Tan
Benzhong Mi

Publication Details

Journal: Afinidad
Published: 2025-09-19
DOI: https://doi.org/10.55815/432522
Primary Topic: Eicosanoids and Hypertension Pharmacology
Type: article
Field-Weighted Citation Impact: 0.00

Controls

|||

ALL TIME

JAN

FEB

MAR

APR

MAY

JUN

JUL

AUG

SEP

OCT

article

N-Methylcantharidimede：Synthesis and Anti-Hepatoma activity

X Qiao, Xiaoling Liu, Zhi-Yi He, Chunbin Tan et al.

Sep 19, 2025

Afinidad

Eicosanoids and Hypertension Pharmacology

article

N-Methylcantharidimede：Synthesis and Anti-Hepatoma activity

X Qiao, Xiaoling Liu, Zhi-Yi He, Chunbin Tan, Benzhong Mi

September 19, 2025article en

Abstract

AfinidadVol. 82(606)

Openalex Percentile: Top 75%

Eicosanoids and Hypertension Pharmacology

DOI Source OpenAlex

AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

N-Methylcantharidimede：Synthesis and Anti-Hepatoma activity — X Qiao, Xiaoling Liu, et al. · Afinidad (2025) | TGRS Research Map | TGRS