Safety of [188RE]Re-Imdendrim in the Treatment of Tumor Indications

The detection of intraoperative stroke is paramount for enhancing patient outcomes during major vascular surgical procedures. Prior studies have demonstrated that alterations in cerebral blood flow (CBF) resulting from surgical interventions can be identified through a variety of neuromonitoring techniques, including electroencephalography, neurophysiological evoked potential assessments, transcranial Doppler ultrasound, and near-infrared spectroscopy. In this report, we present a case involving an open repair for type B aortic dissection that was complicated by extensive, multifocal cerebral infarctions. A notable intraoperative decline in the Patient State Index (PSI) and a concomitant rise in the Suppression Ratio (SR) were observed immediately following the transition of bypass modalities. This decline in PSI did not recover by the conclusion of the surgical procedure, despite only minor fluctuations in blood pressure and cerebral oximetry. Continuous monitoring of the PSI may facilitate the early detection and differentiation of intraoperative strokes, even in the absence of compromised CBF.