Navigating Challenges in Mixed Malaria Infections: A Case of Mixed Plasmodium falciparum and Plasmodium vivax Infection in a Patient With Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency

Malaria continues to be a significant health issue in various regions worldwide, including Malaysia. It is a vector-borne disease transmitted primarily by <i>Anopheles</i> mosquitoes. Mixed malaria infections are rarely reported and often underestimated globally. Early diagnosis is essential for timely treatment, which improves outcomes and reduces morbidity. We report a case of imported mixed malaria infection in a patient with glucose-6-phosphate dehydrogenase deficiency, in whom <i>Plasmodium falciparum</i> and <i>Plasmodium vivax</i> were identified through malaria PCR. The patient's condition improved after completing a full course of IV artesunate, oral Riamet (artemether/lumefantrine), and primaquine.