Ten‐Year Incidence, Risk Factors and Progression Rate of Macular Atrophy in Neovascular Age‐Related Macular Degeneration
nAMD patients treated with PRN anti-VEGF therapy demonstrated a high 10-year cumulative incidence of MA (79.8%), with poor baseline BCVA and CST fluctuations as key risk factors. Eyes with incident MA progressed faster and were associated with greater visual decline, suggesting a more visually impactful atrophy.
Authors
- Marco Casaluci
- Alessandro Invernizzi (ORCID: https://orcid.org/0000-0003-3400-1987)
- Kelvin Yi Chong Teo (ORCID: https://orcid.org/0000-0002-7458-7081)
- Elisa Cozzi
- Francesco Pozzo Giuffrida (ORCID: https://orcid.org/0000-0002-2309-8157)
- Andrea Aretti
- Francesco ROMANO (ORCID: https://orcid.org/0000-0002-1865-6396)
- Matteo Airaldi (ORCID: https://orcid.org/0000-0001-9010-1208)
- Francesco Viola (ORCID: https://orcid.org/0000-0003-1208-913X)
- Paolo Milella (ORCID: https://orcid.org/0000-0002-5295-3730)
- Antonio Valastro (ORCID: https://orcid.org/0009-0003-2834-6142)
- Giovanni Staurenghi (ORCID: https://orcid.org/0000-0002-2299-5251)
- Chui Ming Gemmy Cheung (ORCID: https://orcid.org/0000-0003-3358-3516)
- Marco Nassisi (ORCID: https://orcid.org/0000-0002-9354-9005)
Institutions
- University of Milan (IT)
- Singapore National Eye Center (SG)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Luigi Sacco Hospital (IT)
- Singapore Eye Research Institute (SG)
Publication Details
- Journal
- Clinical and Experimental Ophthalmology
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1111/ceo.14608
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Massachusetts Eye and Ear