Elderly Patients With Glioblastoma and Good Prognostic Factors May Achieve Equivalent Median Survival to Younger Patients When Managed With Standard Long‐Course Rather Than Elderly Protocols

When stratified for performance status and MGMT methylation, elderly patients had similar outcomes compared with the younger cohort. This suggests that elderly patients who managed well following diagnosis and subsequent surgical procedure may be optimally treated with long-course standard rather than elderly protocols.

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Publication Details

Journal
Journal of Medical Imaging and Radiation Oncology
Published
2025-09-19
DOI
https://doi.org/10.1111/1754-9485.70020
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Elderly Patients With Glioblastoma and Good Prognostic Factors May Achieve Equivalent Median Survival to Younger Patients When Managed With Standard Long‐Course Rather Than Elderly Protocols

Patrick Horsley, Anneka Parker, Michael Back, Marina Kastelan et al.
Journal of Medical Imaging and Radiation Oncology
Glioma Diagnosis and Treatment
article

Elderly Patients With Glioblastoma and Good Prognostic Factors May Achieve Equivalent Median Survival to Younger Patients When Managed With Standard Long‐Course Rather Than Elderly Protocols

Patrick Horsley, Anneka Parker, Michael Back, Marina Kastelan, Brendan Liu, Helen Wheeler, V. Venkatesha
article en

Abstract

When stratified for performance status and MGMT methylation, elderly patients had similar outcomes compared with the younger cohort. This suggests that elderly patients who managed well following diagnosis and subsequent surgical procedure may be optimally treated with long-course standard rather than elderly protocols.

Journal of Medical Imaging and Radiation OncologyVol. 69(8)
The University of Sydney (AU), Royal North Shore Hospital (AU), Genesis HealthCare (US), Gosford Hospital (AU), Cancer Australia (AU), Cure Brain Cancer Foundation (AU)
Openalex Percentile: Top 65%
Glioma Diagnosis and Treatment
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Elderly Patients With Glioblastoma and Good Prognostic Factors May Achieve Equivalent Median Survival to Younger Patients When Managed With Standard Long‐Course Rather Than Elderly Protocols — Patrick Horsley, Anneka Parker, et al. · Journal of Medical Imaging and Radiation Oncology (2025) | TGRS Research Map | TGRS