Malignant peripheral nerve sheath tumors in neurofibromatosis type 1 arise from distinct nodular lesions: A retrospective imaging analysis
Most NF1-related MPNST develop from preexisting DNL. However, we cannot estimate what percentage of DNL will transform to MPNST. Assessing the risk of malignant transformation of DNL in NF1 requires prospective studies.
Authors
- Andrea M. Gross (ORCID: https://orcid.org/0000-0003-1646-4531)
- Said Farschtschi (ORCID: https://orcid.org/0000-0002-3596-5932)
- Johannes Salamon
- Victor‐Felix Mautner (ORCID: https://orcid.org/0000-0002-1953-5182)
- Eva Dombi (ORCID: https://orcid.org/0000-0002-5323-6995)
- Brigitte C. Widemann (ORCID: https://orcid.org/0000-0002-9198-7175)
- Andrea Baldwin
Institutions
- Leidos (United States) (US)
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- National Cancer Institute (US)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/noajnl/vdaf201
- Citations
- 2
- Primary Topic
- Neurofibromatosis and Schwannoma Cases
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health