Intracerebral hemorrhage risk in glioma patients taking direct oral anticoagulants as compared with low molecular weight heparin
This observational study suggests DOACs are relatively safe in glioma patients given the low ICH risk. While most ICH events occurred in glioblastoma patients, no significant difference in risk was found across tumor grades. Prospective studies will establish anticoagulation risks in this population.
Authors
- Justin Durla Lathia (ORCID: https://orcid.org/0000-0003-3168-7290)
- Surabhi Ranjan (ORCID: https://orcid.org/0000-0001-7674-870X)
- Glen H. J. Stevens (ORCID: https://orcid.org/0000-0002-0106-8483)
- Alejandro Torres-Trejo
- Mina Lobbous (ORCID: https://orcid.org/0000-0002-7034-2079)
- Andrew Dhawan (ORCID: https://orcid.org/0000-0002-5027-1277)
- Mark G. Malkin (ORCID: https://orcid.org/0000-0001-9546-901X)
- Scott J. Cameron (ORCID: https://orcid.org/0000-0002-9616-1540)
- Matthew M. Grabowski (ORCID: https://orcid.org/0000-0001-8550-0124)
- David M. Peereboom (ORCID: https://orcid.org/0000-0001-7798-5176)
- Anthony Sloan (ORCID: https://orcid.org/0000-0001-7994-3316)
- Radhika S. Amin (ORCID: https://orcid.org/0009-0004-8012-6929)
Institutions
- Cleveland Clinic (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Cleveland Clinic Florida (US)
- University Hospitals Seidman Cancer Center (US)
- Case Comprehensive Cancer Center
- Case Western Reserve University (US)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/noajnl/vdaf205
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cleveland Clinic
- Cleveland Clinic Foundation