Posttransplant Health–economic Impact of Normothermic Machine Perfusion (Back-to-base Model): Advancing Donation After Circulatory Death Liver Transplants With Improved Outcomes and Reduced Wait Times

Use of NMP does not decrease postoperative direct costs after DCD LT. However, with the use of NMP, a greater number of DCD liver grafts can be used, from a broader range of donors, wait time to transplant can be reduced, and waitlist survival can be improved while improving relevant clinical outcomes. The overall cost savings achieved by transplanting patients quickly at low Model for End-stage Liver Disease scores and improving waitlist morbidity should be further explored.

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Publication Details

Journal
Transplantation Direct
Published
2025-09-19
DOI
https://doi.org/10.1097/txd.0000000000001861
Primary Topic
Organ Transplantation Techniques and Outcomes
Type
article
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article

Posttransplant Health–economic Impact of Normothermic Machine Perfusion (Back-to-base Model): Advancing Donation After Circulatory Death Liver Transplants With Improved Outcomes and Reduced Wait Times

Annelise Nolan, April Logan, Ashley Limkemann, Austin D. Schenk et al.
Transplantation Direct
Organ Transplantation Techniques and Outcomes
article

Posttransplant Health–economic Impact of Normothermic Machine Perfusion (Back-to-base Model): Advancing Donation After Circulatory Death Liver Transplants With Improved Outcomes and Reduced Wait Times

Annelise Nolan, April Logan, Ashley Limkemann, Austin D. Schenk, Musab Alebrahim, W. Kenneth Washburn, Ayato Obana, Leonid Gorelik, Sylvester M. Black, Sai Rithin Punjala, Navdeep Singh, Lauren Von Stein, Manoj H. Iyer, Wei Chen
article en

Abstract

Use of NMP does not decrease postoperative direct costs after DCD LT. However, with the use of NMP, a greater number of DCD liver grafts can be used, from a broader range of donors, wait time to transplant can be reduced, and waitlist survival can be improved while improving relevant clinical outcomes. The overall cost savings achieved by transplanting patients quickly at low Model for End-stage Liver Disease scores and improving waitlist morbidity should be further explored.

Transplantation DirectVol. 11(10)
The Ohio State University Wexner Medical Center (US), The Ohio State University (US)
Openalex Percentile: Top 59%
Organ Transplantation Techniques and Outcomes
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Posttransplant Health–economic Impact of Normothermic Machine Perfusion (Back-to-base Model): Advancing Donation After Circulatory Death Liver Transplants With Improved Outcomes and Reduced Wait Times — Annelise Nolan, April Logan, et al. · Transplantation Direct (2025) | TGRS Research Map | TGRS