Early versus deferred antiretroviral therapy initiation and long-term cardiovascular disease outcomes in people with HIV: The START study

Early versus deferred ART initiation was not associated with reduced CVD events. The potential benefit associated with immediate ART in female participants warrants further evaluation.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-08-29
DOI
https://doi.org/10.1093/ofid/ofaf561
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Early versus deferred antiretroviral therapy initiation and long-term cardiovascular disease outcomes in people with HIV: The START study

Andrew N. Phillips, Vicente Estrada, M Kundro, Nila J. Dharan et al.
Open Forum Infectious Diseases
HIV-related health complications and treatments
article

Early versus deferred antiretroviral therapy initiation and long-term cardiovascular disease outcomes in people with HIV: The START study

Andrew N. Phillips, Vicente Estrada, M Kundro, Nila J. Dharan, Jason V. Baker, Tess E. Peterson, Rakan Nasreddine, Janine M. Trevillyan, Gail Matthews, Alejandro Arenas‐Pinto, Daniel A. Duprez, Irini Sereti, Rosie Mngqibisa, Shweta Sharma, Kieu Trang Ha, David J. Munroe
article en

Abstract

Early versus deferred ART initiation was not associated with reduced CVD events. The potential benefit associated with immediate ART in female participants warrants further evaluation.

Open Forum Infectious DiseasesVol. 12(9)
Universidad Complutense de Madrid (ES), National Institutes of Health (US), University of Minnesota (US), Council of Independent Colleges (US), The George Institute for Global Health (GB), University of Minnesota System (US), Advisory Board Company (United States) (US), Hospital Clínico San Carlos (ES), UNSW Sydney (AU), Cooper Medical School of Rowan University (US), MRC Clinical Trials Unit at UCL (GB), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (ES), Hospital Ramos Mejía (AR), Peter Doherty Institute (AU), King Edward VIII Hospital (ZA), National Institute of Allergy and Infectious Diseases (US), Centre for Global Health Research (CA), Minnesota Department of Health (US), Hennepin Healthcare Research Institute (US), Centre Hospitalier Universitaire de Saint-Pierre (BE), Cooper University Health Care (US), Austin Health (AU), Joint Clinical Research Centre (UG), Sydney Orthopaedic Research Institute (AU), University College London (GB)
Bristol-Myers Squibb, GlaxoSmithKline, Styrelsen för Internationellt Utvecklingssamarbete, Gilead Sciences, University of Minnesota, ViiV Healthcare, Janssen Scientific Affairs, National Institute for Health and Care Research, National Research Foundation, Medical Research Council, National Health and Medical Research Council, National Institute of Allergy and Infectious Diseases, European AIDS Treatment Network
Openalex Percentile: Top 62%
HIV-related health complications and treatments
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