CD9: Differential expression of normal bone marrow cellular components and leukemic myeloid blasts

Aberrant CD9 expression can be useful differentiating normal from abnormal myeloid progenitors, with the highest level of expression in AML with PML::RARA in our cohort. There was differential expression between HSCs and CMPs in the small numbers studied. Normal mature B cells can be used as an internal negative control in most cases.

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Publication Details

Journal
American Journal of Clinical Pathology
Published
2025-07-25
DOI
https://doi.org/10.1093/ajcp/aqaf087
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
0.00
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article

CD9: Differential expression of normal bone marrow cellular components and leukemic myeloid blasts

Elizabeth Quirk, Parastou Tizro, Joo Y. Song, Lori Soma et al.
American Journal of Clinical Pathology
Acute Myeloid Leukemia Research
article

CD9: Differential expression of normal bone marrow cellular components and leukemic myeloid blasts

Elizabeth Quirk, Parastou Tizro, Joo Y. Song, Lori Soma, Winston Lee, Afreen Jasim, Huiyan Ma, Jessica R Hughes, Scott Hwee
article en

Abstract

Aberrant CD9 expression can be useful differentiating normal from abnormal myeloid progenitors, with the highest level of expression in AML with PML::RARA in our cohort. There was differential expression between HSCs and CMPs in the small numbers studied. Normal mature B cells can be used as an internal negative control in most cases.

American Journal of Clinical PathologyVol. 164(5)
City Of Hope National Medical Center (US)
Openalex Percentile: Top 66%
Acute Myeloid Leukemia Research
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