Dexmedetomidine and postoperative dementia risk in older patients

This study is the first to provide clinical evidence supporting dexmedetomidine's potential in reducing dementia risk, particularly ad, in older postoperative patients. Further randomised trials are needed to confirm these findings and determine the optimal use of dexmedetomidine in postoperative care. If validated, dexmedetomidine could become a critical strategy in reducing the long-term cognitive burden in ageing populations.

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Publication Details

Journal
Age and Ageing
Published
2025-08-29
DOI
https://doi.org/10.1093/ageing/afaf258
Citations
2
Primary Topic
Cardiac, Anesthesia and Surgical Outcomes
Type
article
Field-Weighted Citation Impact
2.78
Controls
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article

Dexmedetomidine and postoperative dementia risk in older patients

Szu‐Yuan Wu, Mingyang Sun, Shihui Fu, Wan‐Ming Chen et al.
2 citations
Age and Ageing
Cardiac, Anesthesia and Surgical Outcomes
2.78
article

Dexmedetomidine and postoperative dementia risk in older patients

Szu‐Yuan Wu, Mingyang Sun, Shihui Fu, Wan‐Ming Chen, Jiaqiang Zhang, Mao Tian, Wei Li, Xiaojuan Xie, Shengchun Cai
article en
2 citations

Abstract

This study is the first to provide clinical evidence supporting dexmedetomidine's potential in reducing dementia risk, particularly ad, in older postoperative patients. Further randomised trials are needed to confirm these findings and determine the optimal use of dexmedetomidine in postoperative care. If validated, dexmedetomidine could become a critical strategy in reducing the long-term cognitive burden in ageing populations.

Age and AgeingVol. 54(9)
Fu Jen Catholic University (TW), Asia University (TW), Luodong Poh-Ai Hospital (TW), Zhengzhou University (CN), Henan Academy of Sciences (CN), Henan Provincial People's Hospital (CN), First Affiliated Hospital of Henan University of Science and Technology (CN), Wan Fang Hospital (TW)
Openalex Percentile: Top 8%
Cardiac, Anesthesia and Surgical Outcomes
2.78
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