Differences in spinal structural lesions between patients with early axSpA and non-axSpA chronic back pain: 2-year SPACE cohort results
Over 2 years, spinal structural damage typical for axSpA progressed minimally on radiography in axSpA and non-axSpA. On MRI, axSpA showed a significant increase in fat lesions, while non-axSpA had no progression. Fat lesions may be important to assess spinal changes from early disease onwards.
Authors
- Inger Jorid Berg (ORCID: https://orcid.org/0000-0002-8605-5488)
- Mary Lucy Marques (ORCID: https://orcid.org/0000-0002-3071-9425)
- Sofia Exarchou (ORCID: https://orcid.org/0000-0002-9261-7192)
- Gizem Ayan (ORCID: https://orcid.org/0000-0003-1889-9619)
- Manouk de Hooge (ORCID: https://orcid.org/0000-0002-0652-9808)
- Ana Bento da Silva (ORCID: https://orcid.org/0000-0002-8590-8119)
- Liese J. E. de Bruin (ORCID: https://orcid.org/0000-0001-5106-0175)
- Marleen van de Sande (ORCID: https://orcid.org/0000-0003-0966-878X)
- F. van Gaalen (ORCID: https://orcid.org/0000-0001-8448-7407)
- M. van Lunteren (ORCID: https://orcid.org/0000-0002-0601-4863)
- Roberta Ramonda (ORCID: https://orcid.org/0000-0002-9683-8873)
- Sofía Ramiro (ORCID: https://orcid.org/0000-0002-8899-9087)
- M. Reijnierse (ORCID: https://orcid.org/0000-0002-6906-1851)
- Victoria Navarro‐Compán (ORCID: https://orcid.org/0000-0002-4527-852X)
- Désirée M F M van der Heijde (ORCID: https://orcid.org/0000-0002-5781-158X)
Institutions
- Ministry of Health (TR)
- University of Padua (IT)
- Malmö University (SE)
- Leiden University Medical Center (NL)
- Hospital Universitario La Paz (ES)
- Ghent University Hospital (BE)
- Hospitais da Universidade de Coimbra (PT)
- Memorial Ankara Hospital (TR)
- Ankara Numune Eğitim ve Araştırma Hastanesi (TR)
- Diakonhjemmet Hospital (NO)
- Zuyderland Medisch Centrum (NL)
- Amsterdam University Medical Centers (NL)
- University of Coimbra (PT)
- University of Amsterdam (NL)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-09-15
- DOI
- https://doi.org/10.1093/rheumatology/keaf500
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00