Light-field microscopy with entangled photons

Light-field microscopy (LFM) is a 3D microscopy technique whereby volumetric information of a sample is gained in a single shot by simultaneously capturing both position and angular information of light emanating from a sample. Classical LFM designs generally require a trade-off between position and momentum resolution, requiring one to sacrifice resolving power for increased depth of field (DOF). Here, I present a quantum based LFM design that utilizes the inherent correlation between position-momentum entangled photon pairs and does not require this position- momentum resolution trade-off. We demonstrate that a resolving power of 5<i>μ</i>m can be maintained with a DOF of 500<i>μ</i>m, approximately an order of magnitude to that of a classical LFM. In the extreme, at a resolving power of 100<i>μ</i>m, it is possible to achieve near infinite DOF.