Peroxiredoxin 1 inhibits tumorigenesis by activating the NLRP3/GSDMD pathway to induce pyroptosis of colorectal cancer cells
Prdx1 induces pyroptosis by activating the NLRP3 inflammasome/GSDMD pathway, thereby inhibiting the malignant biological behavior of RKO and SW480 colon cancer cells.
Authors
- Ling-Xiang Xie
- Ying He (ORCID: https://orcid.org/0009-0005-9427-0937)
- Chunlan Chen
- Yongfang Jiang (ORCID: https://orcid.org/0000-0001-7415-4289)
- Jing Liu (ORCID: https://orcid.org/0000-0002-7366-5287)
- Ning Zhou (ORCID: https://orcid.org/0000-0001-7492-2014)
Institutions
- Central South University (CN)
- Hunan Normal University (CN)
- Hunan Provincial People's Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-09-18
- DOI
- https://doi.org/10.3748/wjg.v31.i36.111557
- Citations
- 4
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.22