Abstract A149: De Casa En Casa Program: Preventing cervical cancer in West & South Texas

Abstract Purpose: Cervical cancer disproportionately affects minorities and those living in rural and underserved communities. Barriers such as lack of insurance, limited access to primary care, and low health literacy result in delayed screening and diagnosis, contributing to higher morbidity and mortality rates. The De Casa en Casa Program addresses these disparities through a comprehensive cervical cancer prevention strategy implemented in a predominantly Hispanic community. Program Overview: The De Casa En Casa program; De Casa 1 (2014-2017) (PP130083), De Casa 2 (2017-2020) (PP170004), (De Casa 3 (2020-2024) (PP200006) and De Casa 4 (PP230059) (2023-2028)], funded by Cancer Prevention Research Institute of Texas (CPRIT) since 2014, delivers multi-component, bilingual, culturally tailored, evidence-based interventions. Components include: 1) community-based outreach, 2) culturally tailored, theory-based education, 3) no-cost screening for eligible women, 4) patient navigation to connect women to diagnostic services, insurance, and primary care, 5) training for resident/faculty physicians to increase local diagnostic capacity. Methods: The program serves primarily uninsured or underinsured women aged 21–65 years across 61 counties in West and South Texas who have not received a Pap test in the past 3–5 years. Program strategies include health education, screening services, colposcopy, patient navigation, and capacity building. Results: Since its inception, the program has reached 63 counties in West and South Texas, recruited 11,714 women, and completed cervical screenings for 8,668 women, with a screening completion rate of 72%. Provided colposcopy services to 617 women (97% diagnostic completion rate) and diagnosed 12 cervical cancers, all of whom were navigated into treatment. Conclusion: The De Casa en Casa Program demonstrates how long-term, community-engaged, culturally tailored interventions can effectively increase cervical cancer screening and reduce health disparities. Its expansion to over 20% of Texas counties highlights its scalable impact on public health outcomes in vulnerable populations. Citation Format: Priyanka Dadha, Estrella Penna, Pracheta Matharasi, Jennifer Molokwu. De Casa En Casa Program: Preventing cervical cancer in West & South Texas [abstract]. In: Proceedings of the 18th AACR Conference on the Science of Cancer Health Disparities; 2025 Sep 18-21; Baltimore, MD. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2025;34(9 Suppl):Abstract nr A149.