Antibiotic Resistance Profile of Endophytic Bacteria of Leptadenia pyrotechnica Root: A Study from Alwar Region

Antibiotic resistance is a developing issue because it makes infections more difficult to treat, which increases the risk of death, lengthens sickness duration, and raises medical expenses, particularly when the bacteria causing the infection is resistant to numerous medications. In present study, we examined antibiotic resistance profile of endophytic bacteria from the roots of the Indian desert shrub Leptadenia pyrotechnica. This plant is well-known for both its capacity to improve the environment in arid regions and its health advantages. Twelve bacterial samples taken from the roots of the plant were tested against a variety of antibiotics, such as azithromycin, ciprofloxacin, and tetracycline. The findings demonstrated that the bacteria were susceptible to the antibiotics ciprofloxacin and gatifloxacin, which may be effective; however, the bacteria were resistant to other antibiotics, such as ampicillin, ceftriaxone, and azithromycin, indicating the need for novel treatments, including the use of plant-based compounds.