The Potential of Magnetic Targeted Natural Killer Cell Therapy for Glioblastoma: An in Vivo Study of Natural Killer Cells Loaded With Low-Temperature Synthesized Folic Acid–Modified Superparamagnetic Iron Oxide Nanoparticles
SPIONs-PEG-FA-loaded NK cells represent a promising approach for targeted GBM therapy. Their successful synthesis and characterization, coupled with in vitro and in vivo validation, highlight their potential for improved therapeutic outcomes. This magnetic field-guided NK cell therapy offers a promising strategy for overcoming challenges in GBM treatment.
Authors
- Wei‐Ting Kuo (ORCID: https://orcid.org/0000-0002-1230-0014)
- Fon-Yih Tsuang (ORCID: https://orcid.org/0000-0001-5797-1885)
- Feng‐Huei Lin (ORCID: https://orcid.org/0000-0002-2994-6671)
- Ya‐Jyun Liang (ORCID: https://orcid.org/0000-0002-3353-1524)
- Pao‐Chun Lin (ORCID: https://orcid.org/0000-0001-5389-5192)
Institutions
- Fu Jen Catholic University (TW)
- National Health Research Institutes (TW)
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-09-19
- DOI
- https://doi.org/10.1227/neu.0000000000003731
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00