The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

GLS and PDHA1 have been proposed as potential prognostic markers for immunotherapy. Targeting cuproptosis has the potential to convert immunologically cold to hot tumours, thereby advancing precision immunotherapy.

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Publication Details

Journal
Frontiers in Genetics
Published
2025-09-19
DOI
https://doi.org/10.3389/fgene.2025.1606111
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

Thai‐Yen Ling, Jiahui Wu, Ling Xiaohao
Frontiers in Genetics
Ferroptosis and cancer prognosis
article

The potential impact of GLS and PDHA1 on tumor immunity and immunotherapy response in LUSC

Thai‐Yen Ling, Jiahui Wu, Ling Xiaohao
article en

Abstract

GLS and PDHA1 have been proposed as potential prognostic markers for immunotherapy. Targeting cuproptosis has the potential to convert immunologically cold to hot tumours, thereby advancing precision immunotherapy.

Frontiers in GeneticsVol. 16
Guangzhou University of Chinese Medicine (CN), Zhongshan Hospital (CN), Boai Hospital of Zhongshan (CN)
Guangzhou Medical University
Openalex Percentile: Top 63%
Ferroptosis and cancer prognosis
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