Biomarkers in blood and saliva to screen fragile patients with solid tumors: A systematic review of the literature

There are currently no established blood or salivary biomarkers for frailty. However, an elevated inflammatory status and related markers are often significantly correlated with frailty in solid tumor patients. These findings highlight the potential to develop suitable biomarkers for frail oncology patients, emphasizing the need for further research in this area.

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Publication Details

Journal
Critical Reviews in Oncology/Hematology
Published
2025-09-16
DOI
https://doi.org/10.1016/j.critrevonc.2025.104939
Primary Topic
Childhood Cancer Survivors' Quality of Life
Type
article
Field-Weighted Citation Impact
0.00
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article

Biomarkers in blood and saliva to screen fragile patients with solid tumors: A systematic review of the literature

Lorena Cascant Ortolano, Annette Hasenburg, Valerie Catherine Linz, Walburgis Brenner et al.
Critical Reviews in Oncology/Hematology
Childhood Cancer Survivors' Quality of Life
article

Biomarkers in blood and saliva to screen fragile patients with solid tumors: A systematic review of the literature

Lorena Cascant Ortolano, Annette Hasenburg, Valerie Catherine Linz, Walburgis Brenner, Sophia Minou Herzog
article en

Abstract

There are currently no established blood or salivary biomarkers for frailty. However, an elevated inflammatory status and related markers are often significantly correlated with frailty in solid tumor patients. These findings highlight the potential to develop suitable biomarkers for frail oncology patients, emphasizing the need for further research in this area.

Critical Reviews in Oncology/HematologyVol. 216
Johannes Gutenberg University Mainz (DE), University Medical Center of the Johannes Gutenberg University Mainz (DE)
Openalex Percentile: Top 64%
Childhood Cancer Survivors' Quality of Life
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