Genetically predicted plasma metabolites mediate the causal role of immune cells in atrial fibrillation
The results point to a potential major role for immune cells and plasma metabolites in the initiation and progression of AF. For the purpose of preventing and treating AF, these findings could offer novel biomarkers or therapeutic targets in the unclarified pathogenesis of atrial fibrillation, particularly for immune-related pathways.
Authors
- Shan Lu
- Korff Krause
- Yichao Yu (ORCID: https://orcid.org/0000-0003-1838-6688)
- Jiän Zhang (ORCID: https://orcid.org/0000-0002-0557-886X)
- Kejiang Cao
- Yun Liu (ORCID: https://orcid.org/0000-0003-4377-1211)
- Stefan Zarsteck
Institutions
- Nanjing Maternity and Child Health Care Hospital (CN)
- Agaplesion Diakonieklinikum Rotenburg (DE)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Cytokine
- Published
- 2025-09-16
- DOI
- https://doi.org/10.1016/j.cyto.2025.157028
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00