Iron induces <i>Aspergillus</i> proteases in cystic fibrosis allergic bronchopulmonary aspergillosis
These findings suggest that airway iron is a potent stimulus for Af proteases and represents a modifiable risk factor and potential therapeutic target for CF-ABPA.
Authors
- Wayland Chiu (ORCID: https://orcid.org/0000-0001-6992-3020)
- Aijaz Ahmad (ORCID: https://orcid.org/0000-0003-2845-0727)
- David A. Stevens (ORCID: https://orcid.org/0000-0002-5861-5716)
- Amer Ali Abd El‐Hafeez (ORCID: https://orcid.org/0000-0002-4822-6581)
- Efthymia Iliana Matthaiou (ORCID: https://orcid.org/0000-0002-0907-0203)
- Carlos Milla (ORCID: https://orcid.org/0000-0001-5515-3053)
- Joe L. Hsu (ORCID: https://orcid.org/0000-0002-7050-6504)
- Beate Illek (ORCID: https://orcid.org/0000-0003-0076-3553)
- Paulami Chatterjee (ORCID: https://orcid.org/0000-0002-2204-5459)
- Ekroop Dhillon
Institutions
- University of San Diego (US)
- University of California San Diego (US)
- Albany College of Pharmacy and Health Sciences (US)
- Albany Research Institute (US)
- Stanford Medicine (US)
- Albany Medical Center Hospital (US)
- Stanford University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- American Journal of Respiratory Cell and Molecular Biology
- Published
- 2025-09-18
- DOI
- https://doi.org/10.1165/rcmb.2025-0077oc
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00