Asenapine for aggressive behaviours in psychiatric disorders: a systematic review of efficacy and real-world effectiveness

Asenapine may be a viable option for the treatment of psychomotor agitation and hostility, although more head-to-head trials are needed to clarify its efficacy relative to other antipsychotics. Since the evidence of efficacy in other aggressive domains and diagnoses is still limited, clinicians should primarily consider the tolerability profile to guide their prescription.

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Publication Details

Journal
International Journal of Psychiatry in Clinical Practice
Published
2025-09-18
DOI
https://doi.org/10.1080/13651501.2025.2560357
Citations
1
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
1.47
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article

Asenapine for aggressive behaviours in psychiatric disorders: a systematic review of efficacy and real-world effectiveness

Giuseppe Fanelli, Chiara Fabbri, Alessandro Serretti, Mauro Scala
1 citations
International Journal of Psychiatry in Clinical Practice
Schizophrenia research and treatment
1.47
article

Asenapine for aggressive behaviours in psychiatric disorders: a systematic review of efficacy and real-world effectiveness

Giuseppe Fanelli, Chiara Fabbri, Alessandro Serretti, Mauro Scala
article en
1 citations

Abstract

Asenapine may be a viable option for the treatment of psychomotor agitation and hostility, although more head-to-head trials are needed to clarify its efficacy relative to other antipsychotics. Since the evidence of efficacy in other aggressive domains and diagnoses is still limited, clinicians should primarily consider the tolerability profile to guide their prescription.

International Journal of Psychiatry in Clinical PracticeVol. 29(4)
Universidad Complutense de Madrid (ES), Radboud University Nijmegen (NL), Università degli Studi di Enna Kore (IT), University Medical Center (US), Radboud University Medical Center (NL), Research Institute Hospital 12 de Octubre (ES), Oasi Maria SS (IT), Osato Research Institute (JP), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Universidad Europea de Madrid (ES), University of Bologna (IT)
Openalex Percentile: Top 15%
Schizophrenia research and treatment
1.47
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Asenapine for aggressive behaviours in psychiatric disorders: a systematic review of efficacy and real-world effectiveness — Giuseppe Fanelli, Chiara Fabbri, et al. · International Journal of Psychiatry in Clinical Practice (2025) | TGRS Research Map | TGRS