Novel zwitterionic densely charged neutral sulfobetaine polymeric micelles for oral delivery of therapeutic peptides: a proof-of-concept study
Densely charged but neutral sulfobetaine polymeric micelles (PMs) were designed with the aim of efficiently permeating the intestinal mucus and releasing the intact peptide cargo close to the intestinal epithelial surface.
Authors
- Salvador Borrós (ORCID: https://orcid.org/0000-0002-4003-0381)
- Muthanna Abdulkarim (ORCID: https://orcid.org/0000-0001-5753-7261)
- Andreas Bernkop‐Schnürch (ORCID: https://orcid.org/0000-0003-4187-8277)
- Flavia Laffleur (ORCID: https://orcid.org/0000-0002-2827-6741)
- Víctor Ramos (ORCID: https://orcid.org/0000-0002-2099-5557)
Institutions
- Alfaisal University (SA)
- Universität Innsbruck (AT)
- Hospital General de Catalunya (ES)
- Institut Químic de Sarrià (ES)
- Cardiff University (GB)
Publication Details
- Journal
- RSC Pharmaceutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4pm00202d
- Citations
- 2
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 1.58