Physiological substantiation of the effect of mechanical impact on internal organs (literature review)

The relevance of this article is due to the desire to expand the understanding of osteopathic methods of treatment, which, according to the principles of osteopathic medicine, can not only improve the function of the musculoskeletal system, but also positively affect the work of internal organs, contributing to the prevention of their diseases. The data of studies devoted to the mechanosensitivity of cells of various organs and tissues, primarily due to the work of mechanosensitive ion channels (piezo channels), are presented. Despite the accumulated knowledge of the clinical manifestations of somatic disfunction, the relationship of these disorders to plastic and regulatory changes in visceral organs requires further investigation. Understanding how somatic disfunction affects these processes may significantly enrich our knowledge of the therapeutic effects of osteopathic treatment and other physical modalities, as well as their potential in the prevention of various diseases.